Yes, according to new OFP player Kenneth. He's got mod folders and desktop shortcuts set up to run OFP with practically any combination of three different soundpack addons he's installed.
Kenneth says combing Satchel's Dynamic Range soundpack and LDD Kyllikki's soundpack is a winning combination! For lowering overhead in CPU intensive missions, he switches to Munger's Battlesounds soundpack.
IMPORTANT: Using a sound pack addon may affect your ability to participate in MP games. Read about it here.